Congenital toxoplasmosis after a preconceptional or periconceptional maternal infection

Pediatr Infect Dis J. 2009 Jul;28(7):660-1. doi: 10.1097/INF.0b013e3181966020.

Abstract

We report a case of asymptomatic congenital toxoplasmosis following a periconceptional infection of the mother. Fetal infection is very uncommon in such a situation, and mostly associated with fetal damage. We recommend that newborns undergo postnatal screening, even after maternal periconceptional infection, and receive specific therapy to reduce long-term sequelae.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Antibodies, Protozoan / blood
  • Antiprotozoal Agents / therapeutic use
  • DNA, Protozoan / genetics
  • DNA, Protozoan / isolation & purification
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Infant, Newborn
  • Infectious Disease Transmission, Vertical*
  • Male
  • Placenta / parasitology
  • Polymerase Chain Reaction
  • Pregnancy
  • Pregnancy Complications, Parasitic / diagnosis*
  • Pregnancy Complications, Parasitic / drug therapy
  • Spiramycin / therapeutic use
  • Toxoplasma / isolation & purification
  • Toxoplasmosis / diagnosis*
  • Toxoplasmosis / drug therapy
  • Toxoplasmosis / transmission*
  • Toxoplasmosis, Congenital / diagnosis*
  • Toxoplasmosis, Congenital / drug therapy
  • Treatment Outcome

Substances

  • Antibodies, Protozoan
  • Antiprotozoal Agents
  • DNA, Protozoan
  • Immunoglobulin G
  • Spiramycin