Abstract
Clostridium difficile isolates from presumed community-associated infections (n = 92) were characterized by toxinotyping, pulsed-field gel electrophoresis, tcdC and cdtB PCR, and antimicrobial susceptibility. Nine toxinotypes (TOX) and 31 PFGE patterns were identified. TOX 0 (48, 52%), TOX III (18, 20%), and TOX V (9, 10%) were the most common; three isolates were nontoxigenic.
MeSH terms
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ADP Ribose Transferases / genetics
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Bacterial Proteins / genetics
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Bacterial Toxins / analysis
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Bacterial Typing Techniques
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Clostridioides difficile / classification*
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Clostridioides difficile / isolation & purification*
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Cluster Analysis
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Community-Acquired Infections / microbiology*
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DNA Fingerprinting
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Electrophoresis, Gel, Pulsed-Field
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Enterocolitis, Pseudomembranous / microbiology*
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Genotype
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Humans
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Microbial Sensitivity Tests
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Molecular Epidemiology
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Polymerase Chain Reaction / methods
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Repressor Proteins / genetics
Substances
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Bacterial Proteins
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Bacterial Toxins
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Repressor Proteins
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TcdC protein, Clostridium difficile
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ADP Ribose Transferases
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actin-specific ADP-ribosyltransferase, Clostridium