Abstract
We have observed highly polarized and directional surface plasmon-coupled emission of a signaling aptamer due to the binding of a target thrombin with the aptamer, which induces conformational switching.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Aptamers, Nucleotide / chemistry*
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Aptamers, Nucleotide / genetics
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Aptamers, Nucleotide / metabolism
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Base Sequence
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Gold / chemistry
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Nucleic Acid Conformation / drug effects*
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Spectrometry, Fluorescence
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Surface Plasmon Resonance
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Surface Properties
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Thrombin / metabolism
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Thrombin / pharmacology
Substances
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Aptamers, Nucleotide
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Gold
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Thrombin