Abstract
In this work, we report novel fibrin targeted "soft-type" manganese-based contrast agents for MRI with the potential to noninvasively image intravascular thrombus which could warrant aggressive medical intervention to preclude subsequent myocardial infarction or stroke.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Colloids
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Contrast Media / chemistry
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Contrast Media / metabolism
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Fibrin / metabolism*
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Magnetic Resonance Imaging
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Manganese / chemistry*
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Manganese / metabolism*
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Manganese Compounds / chemistry
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Manganese Compounds / metabolism
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Nanostructures / chemistry*
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Oleic Acid / chemistry
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Oleic Acid / metabolism
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Oxides / chemistry
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Oxides / metabolism
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Sensitivity and Specificity
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Substrate Specificity
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Thrombosis / diagnosis*
Substances
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Colloids
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Contrast Media
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Manganese Compounds
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Oxides
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Oleic Acid
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Manganese
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manganese oxide
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Fibrin