Abstract
Three new (1-3) and four known (4-7) compounds were isolated from the stems of Baccaurea ramiflora. By analysis of 1D, 2D NMR, and MS data, the new compounds were identified as 4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D (1), 6'-O-vanilloylpicraquassioside D (2), and 6'-O-vanilloylicariside B(5) (3). Compound 1 exhibited significant DPPH radical-scavenging activity, with an IC(50) value of 36.9 microM, while compound 4 revealed weak antioxidant activity against H (2)O(2)-induced impairment in PC12 cells.
Copyright Georg Thieme Verlag KG Stuttgart . New York.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antioxidants / isolation & purification*
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Antioxidants / pharmacology
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Biphenyl Compounds
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Disaccharides / isolation & purification*
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Disaccharides / pharmacology
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Hydrogen Peroxide
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Inhibitory Concentration 50
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Magnoliopsida / chemistry*
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Monosaccharides / isolation & purification*
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Monosaccharides / pharmacology
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PC12 Cells
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Picrates
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Plant Extracts / chemistry*
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Plant Extracts / pharmacology
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Plant Stems
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Rats
Substances
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4'-O-(6- O-vanilloyl)-beta-D-glucopyranosyl tachioside D
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6'-O-vanilloylicariside B5
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6'-O-vanilloylpicraquassioside D
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Antioxidants
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Biphenyl Compounds
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Disaccharides
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Monosaccharides
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Picrates
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Plant Extracts
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Hydrogen Peroxide
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1,1-diphenyl-2-picrylhydrazyl