Abstract
Florfenicol resistance was analyzed in 230 enteric pig isolates collected between 1998 and 2006. PCR, plasmid profiling, Southern blot hybridization, and a mixed-broth conjugation assay suggested the intra- and interspecies plasmid-mediated transfer of florfenicol resistance among the isolates that exhibited MICs for florfenicol between 4 to 128 mg/liter.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Anti-Bacterial Agents / pharmacology*
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Blotting, Southern
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Conjugation, Genetic
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DNA, Bacterial / genetics
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Drug Resistance, Bacterial*
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Enterobacteriaceae / drug effects*
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Enterobacteriaceae / genetics*
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Enterobacteriaceae / isolation & purification
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Gene Transfer, Horizontal*
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Plasmids*
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Polymerase Chain Reaction
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Swine / microbiology*
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Thiamphenicol / analogs & derivatives*
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Thiamphenicol / pharmacology
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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florfenicol
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Thiamphenicol