Abstract
The tert-butyl N-hydroxycarbamate-derived nitroso reagent 1 reacted with N-Cbz-protected spirocyclic diene 2 to provide spirocycloadduct 3. Here we describe the efficient conversion of 3 into the novel carbocyclic nucleoside spironoraristeromycin 4.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adenosine / analogs & derivatives*
-
Adenosine / chemical synthesis
-
Adenosine / chemistry
-
Models, Molecular
-
Molecular Conformation
-
Nitroso Compounds / chemistry*
-
Stereoisomerism
-
Substrate Specificity
Substances
-
Nitroso Compounds
-
5'-noraristeromycin
-
Adenosine