Abstract
T follicular helper (Tfh) cells are crucial for generating humoral immune responses. In this issue of Immunity, Schmitt et al. (2009) reveal the differentiation of human Tfh cells is dependent on dendritic cell-derived interleukin-12.
MeSH terms
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Animals
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Cell Differentiation / immunology
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Cytokines / immunology*
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Cytokines / metabolism
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Dendritic Cells / immunology*
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Dendritic Cells / metabolism
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Humans
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Interleukin-12 / immunology*
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Interleukin-12 / metabolism
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T-Lymphocyte Subsets / immunology*
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T-Lymphocyte Subsets / metabolism
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T-Lymphocytes, Helper-Inducer / immunology*
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T-Lymphocytes, Helper-Inducer / metabolism