Abstract
Ninety-six clinical isolates of Staphylococcus aureus from Nigeria were characterized phenotypically and genetically. Twelve multidrug-resistant methicillin (meticillin)-resistant S. aureus (MRSA) isolates carrying a new staphylococcal cassette chromosome mec element and a high proportion of Panton-Valentine leukocidin (PVL)-positive methicillin-susceptible S. aureus (MSSA) isolates were observed. The cooccurrence of multidrug-resistant MRSA and PVL-positive MSSA isolates entails the risk of emergence of a multidrug-resistant PVL-positive MRSA clone.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacterial Toxins / genetics*
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Bacterial Typing Techniques / methods
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Cluster Analysis
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DNA Fingerprinting / methods
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Drug Resistance, Multiple, Bacterial*
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Exotoxins / genetics*
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Genotype
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Hospitals
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Humans
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Leukocidins / genetics*
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Molecular Epidemiology
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Nigeria
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Staphylococcal Infections / microbiology*
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Staphylococcus aureus / classification*
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Staphylococcus aureus / genetics
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Staphylococcus aureus / isolation & purification*
Substances
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin