Decrease of skin infiltrating and circulating CCR10+ T cells coincides with clinical improvement after topical tacrolimus in Omenn syndrome

J Invest Dermatol. 2010 Jan;130(1):308-11. doi: 10.1038/jid.2009.196.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Topical
  • Humans
  • Immunosuppressive Agents / pharmacology*
  • Male
  • Receptors, CCR10 / metabolism
  • Severe Combined Immunodeficiency / drug therapy*
  • Severe Combined Immunodeficiency / immunology*
  • T-Lymphocytes / cytology
  • T-Lymphocytes / drug effects*
  • T-Lymphocytes / metabolism
  • Tacrolimus / pharmacology*
  • Treatment Outcome

Substances

  • CCR10 protein, human
  • Immunosuppressive Agents
  • Receptors, CCR10
  • Tacrolimus