NMR assignment of the C-terminal actin-binding domain of talin

Biomol NMR Assign. 2008 Jun;2(1):17-9. doi: 10.1007/s12104-007-9073-5. Epub 2007 Dec 22.

Abstract

Talin is a large dimeric 270 kDa adapter protein which binds the cytoplasmic face of a subset of integrin beta-subunits and couples them to the actin cytoskeleton. Here we report the near complete 15N, 13C and 1H chemical shift assignments for the C-terminal actin-binding domain.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actins / chemistry*
  • Amino Acid Sequence
  • Binding Sites
  • Carbon Isotopes / chemistry
  • Magnetic Resonance Spectroscopy / methods*
  • Molecular Sequence Data
  • Molecular Weight
  • Nitrogen Isotopes / chemistry
  • Protein Binding
  • Protons
  • Talin / chemistry*

Substances

  • Actins
  • Carbon Isotopes
  • Nitrogen Isotopes
  • Protons
  • Talin