Dose reduction in spiral CT coronary angiography with dual-source equipment. Part I. A phantom study applying different prospective tube current modulation algorithms

Radiol Med. 2009 Oct;114(7):1037-52. doi: 10.1007/s11547-009-0437-z. Epub 2009 Aug 7.

Abstract

Purpose: The authors sought to compare different algorithms for dose reduction in retrospectively echocardiographically (ECG)-gated dual-source computed tomography (CT) coronary angiography (DSCT-CA) in a phantom model.

Materials and methods: Weighted CT dose index (CTDI) was measured by using an anthropomorphic phantom in spiral cardiac mode (retrospective ECG gating) at five pitch values adapted with two heart-rate-adaptive ECG pulsing windows using four algorithms: narrow pulsing window, with tube current reduction to 20% (A) and 4% (B) of peak current outside the pulsing window; wide pulsing window, with tube current reduction to 20% (C) and 4% (D). Each algorithm was applied at different heart rates (45, 60, 75, 90, 120 bpm).

Results: Mean CTDI volume (CTDIvol) was 36.9+/-9.7 mGy, 23.9+/-5.6 mGy, 49.7+/-16.2 mGy and 38.5+/-12.3 mGy for A, B, C and D, respectively. Consistent dose reduction was observed with protocols applying the 4% tube current reduction (B and D). Using the conversion coefficient for the chest, the mean effective dose was the highest for C (9.6 mSv) and the lowest for B (4.6 mSv). Heart-ratedependent pitch values (pitch=0.2, 0.26, 0.34, 0.43, 0.5) and the use of heart-rate-adaptive ECG pulsing windows provided a significant decrease in the CTDIvol with progressively higher heart rates (45, 60, 75, 90, 120 bpm), despite using wider pulsing windows.

Conclusions: Radiation exposure with DSCT-CA using a narrow pulsing window significantly decreases when compared with a wider pulsing window. When using a protocol with reduced tube current to 4%, the radiation dose is significantly lower.

Publication types

  • Comparative Study

MeSH terms

  • Absorptiometry, Photon
  • Algorithms
  • Coronary Angiography / instrumentation*
  • Coronary Angiography / methods
  • Electrocardiography*
  • Equipment Design
  • Heart / diagnostic imaging
  • Heart Rate*
  • Humans
  • Models, Theoretical
  • Phantoms, Imaging*
  • Radiation Dosage*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Thermoluminescent Dosimetry
  • Tomography, Spiral Computed*