PEGylation modulates the interfacial kinetics of proteases on peptide-capped gold nanoparticles

Chem Commun (Camb). 2009 Sep 7:(33):5009-11. doi: 10.1039/b910657j. Epub 2009 Jul 13.

Abstract

Fluorescence unquenching measurements of protease-dependent release of fluorescent biomolecules from peptide-capped gold nanoparticles reveal the effect of the monolayer composition on enzyme kinetics.

MeSH terms

  • Amino Acid Sequence
  • Fluorescent Dyes / chemistry
  • Gold / chemistry*
  • Kinetics
  • Metal Nanoparticles / chemistry*
  • Metal Nanoparticles / ultrastructure
  • Molecular Sequence Data
  • Peptide Hydrolases / metabolism*
  • Peptides / analysis
  • Peptides / chemistry*
  • Polyethylene Glycols / chemistry*

Substances

  • Fluorescent Dyes
  • Peptides
  • Polyethylene Glycols
  • Gold
  • Peptide Hydrolases