Abstract
Long thought to be the glue responsible for holding sister chromatids together, cohesin has been found to be stickier than previously thought. Recent discoveries point to cohesin having a role in transcription regulation by mediating long-distance intra-chromosomal interactions.
MeSH terms
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Animals
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CCCTC-Binding Factor
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Cell Cycle Proteins / metabolism*
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Chromatin / metabolism*
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Chromosomal Proteins, Non-Histone / metabolism*
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Cohesins
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Gene Expression Regulation
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Humans
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Interphase
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Models, Biological
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Repressor Proteins / metabolism
Substances
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CCCTC-Binding Factor
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CTCF protein, human
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Cell Cycle Proteins
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Chromatin
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Chromosomal Proteins, Non-Histone
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Repressor Proteins