Abstract
Carbapenem-resistant isolates of Acinetobacter baumannii from intensive care units at Split University Hospital, Split, Croatia, were studied. Most (100 of 106) had ISAba1 inserted upstream of a bla(OXA-107) gene, encoding an unusual OXA-51-type oxacillinase. Pulsed-field gel electrophoresis revealed that the isolates formed three clusters belonging to the sequence group 2 (European clone 1) lineage.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acinetobacter Infections / microbiology*
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Acinetobacter baumannii / classification
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Acinetobacter baumannii / drug effects*
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Acinetobacter baumannii / enzymology*
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Acinetobacter baumannii / isolation & purification
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Adolescent
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Adult
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Aged
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Aged, 80 and over
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Anti-Bacterial Agents / pharmacology*
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Bacterial Typing Techniques
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Carbapenems / pharmacology*
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Child
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Child, Preschool
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Cluster Analysis
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Croatia
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Electrophoresis, Gel, Pulsed-Field
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Female
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Genotype
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Humans
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Infant
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Infant, Newborn
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Intensive Care Units
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Male
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Middle Aged
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Molecular Epidemiology
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Molecular Sequence Data
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Young Adult
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beta-Lactam Resistance*
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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Carbapenems
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beta-Lactamases