Non-small cell lung cancer presenting with neoplastic fever at diagnosis and relapse

Y K Zee; R A Soo

doi:10.1016/j.ijid.2009.06.009

Non-small cell lung cancer presenting with neoplastic fever at diagnosis and relapse

Int J Infect Dis. 2010 Jun;14(6):e518-21. doi: 10.1016/j.ijid.2009.06.009. Epub 2009 Aug 21.

Authors

Y K Zee¹, R A Soo

Affiliation

¹ National University Cancer Institute Singapore, National University Health System, 5 Lower Kent Ridge Road, Singapore 119074, Singapore. [email protected]

PMID: 19699672
DOI: 10.1016/j.ijid.2009.06.009

Abstract

Fever occurs frequently in cancer patients, and neoplastic fever is a well-described paraneoplastic phenomenon in patients with lymphoma, acute leukemias, and renal cell carcinoma. It is also more commonly encountered in metastatic disease. Treatment options include disease-specific therapy, non-steroidal anti-inflammatory drugs (NSAIDs), and steroids. Lung cancer is one of the most common cancers, yet fever as a manifestation of this malignancy has not been emphasized. In this report, we describe an unusual case of non-metastatic non-small cell lung cancer (NSCLC) presenting with neoplastic fever at both diagnosis and relapse, responding on each occasion to disease-specific treatment, and provide a review of the management of neoplastic fever.

Publication types

Case Reports

MeSH terms

Adult
Carcinoma, Non-Small-Cell Lung / diagnosis*
Carcinoma, Non-Small-Cell Lung / radiotherapy
Carcinoma, Non-Small-Cell Lung / surgery
Fever / diagnosis*
Humans
Lung Neoplasms / diagnosis*
Lung Neoplasms / radiotherapy
Lung Neoplasms / surgery
Male
Neoplasm Recurrence, Local / diagnosis*
Treatment Outcome