[Limbic encephalitis associated to voltage dependent potassium channel antibodies: report of one case]

Rev Med Chil. 2009 May;137(5):675-9. Epub 2009 Jul 17.
[Article in Spanish]

Abstract

Limbic encephalitis (LE) can be associated to cancer, viral infection or be idiopathic. One form is associated to voltage dependent potassium channel (VKC) antibodies. The clinical presentation includes impairment of consciousness, amnesia and temporal lobe seizures; typical abnormalities are also found in brain magnetic resonance. We report a 68 year-old male who had LE associated to VKC antibodies. The patient was treated with steroids with a partial response. At the moment of the report he is asymptomatic and continues with prednisone treatment .

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Autoantibodies / blood*
  • Electroencephalography
  • Glucocorticoids / therapeutic use
  • Humans
  • Levetiracetam
  • Limbic Encephalitis / diagnosis
  • Limbic Encephalitis / drug therapy
  • Limbic Encephalitis / immunology*
  • Magnetic Resonance Imaging
  • Male
  • Piracetam / analogs & derivatives
  • Piracetam / therapeutic use
  • Potassium Channels, Voltage-Gated / immunology*
  • Prednisone / therapeutic use
  • Tomography, X-Ray Computed
  • Valproic Acid / therapeutic use

Substances

  • Autoantibodies
  • Glucocorticoids
  • Potassium Channels, Voltage-Gated
  • Levetiracetam
  • Valproic Acid
  • Prednisone
  • Piracetam