MRI of gastric carcinoma: results of T and N-staging in an in vitro study

World J Gastroenterol. 2009 Aug 28;15(32):3992-8. doi: 10.3748/wjg.15.3992.

Abstract

Aim: To determine the accuracy of 1.5-T magnetic resonance imaging (MRI) in the evaluation of gastric wall invasion and perigastric lymph node metastasis in gastric adenocarcinoma.

Methods: Twenty resected gastric specimens containing 20 tumors were studied with a 1.5-T MR system using a commercial head surface coil. MR scanning was performed with a T1 weighted image (TR/TE = 500/20), and a T2 weighted image (TR/TE = 2500/90). MR findings were compared with pathologic findings.

Results: A T1-weighted image demonstrated three layers in the normal gastric wall. All of the gastric tumors were well demonstrated by lesions and location. In a MRI findings of gastric wall invasion, there was 1 case of T1, 7 of T2, 11 of T3. Pathologic results of resected specimens included 3 cases of pT1, 4 of pT2, and 12 of pT3. The accuracy of T staging with MRI was 74% (14 of 19). MRI findings of lymph node metastasis included 6 cases of N0, 13 cases of N1. The accuracy of the N staging with MRI was 47% (9 of 19).

Conclusion: MRI has a high diagnostic accuracy in the evaluation of the T staging of gastric cancer in vitro and thus potentially enables preoperative histopathologic staging.

MeSH terms

  • Adenocarcinoma
  • Adult
  • Aged
  • Carcinoma / diagnosis*
  • Carcinoma / pathology*
  • Female
  • Humans
  • In Vitro Techniques
  • Lymphatic Metastasis
  • Magnetic Resonance Imaging / methods*
  • Male
  • Medical Oncology / methods
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Staging
  • Reproducibility of Results
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / pathology*