Impact of xerostomia on the quality of life of adolescents with type 1 diabetes mellitus

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Sep;108(3):376-82. doi: 10.1016/j.tripleo.2009.05.005.

Abstract

Objective: To evaluate the impact of xerostomia on the quality of life (QOL) of adolescents with type 1 diabetes mellitus (DM1).

Study design: The sample was comprised of 51 adolescents with DM1. Diabetic status was determined by glycosylated hemoglobin (HbG) and capillary glucose (CG) tests. Poor metabolic control was defined as HbG >8.0% and CG <90 mg/dL or >130 mg/dL. Measurement of salivary flow was performed by means of stimulated saliva collection. Xerostomia was detected by asking a question about the sensation of having "dry mouth," and OHIP-14 was used to measure the impact of xerostomia on QOL.

Results: A total of 52.9% of subjects presented with xerostomia and 40.8% with hyposalivation. Significant differences between the subjects with and without xerostomia regarding metabolic control levels were not observed (P > .05). However, OHIP-14 scores were significantly different between the subjects with and without xerostomia (P < .001).

Conclusions: Xerostomia is frequent and has a negative impact on QOL of adolescents with DM1.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Blood Glucose / analysis
  • Cross-Sectional Studies
  • Deglutition / physiology
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / psychology*
  • Drinking / physiology
  • Eating / physiology
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Interpersonal Relations
  • Male
  • Quality of Life*
  • Saliva / metabolism
  • Secretory Rate / physiology
  • Social Adjustment
  • Speech / physiology
  • Stress, Physiological / physiology
  • Taste / physiology
  • Xerostomia / physiopathology
  • Xerostomia / psychology*
  • Young Adult

Substances

  • Blood Glucose
  • Glycated Hemoglobin A