Met amplification and HSP90 inhibitors

Cell Cycle. 2009 Sep 1;8(17):2682. Epub 2009 Sep 1.
No abstract available

Publication types

  • Comment
  • News

MeSH terms

  • Apoptosis
  • Benzoquinones / pharmacology*
  • Gene Amplification
  • HSP90 Heat-Shock Proteins / antagonists & inhibitors*
  • HSP90 Heat-Shock Proteins / metabolism
  • Humans
  • Indoles / pharmacology
  • Lactams, Macrocyclic / pharmacology*
  • Piperazines / pharmacology
  • Proto-Oncogene Proteins c-met / antagonists & inhibitors
  • Proto-Oncogene Proteins c-met / genetics
  • Proto-Oncogene Proteins c-met / metabolism*
  • Sulfonamides / pharmacology
  • Tumor Cells, Cultured

Substances

  • ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide)
  • Benzoquinones
  • HSP90 Heat-Shock Proteins
  • Indoles
  • Lactams, Macrocyclic
  • Piperazines
  • Sulfonamides
  • tanespimycin
  • Proto-Oncogene Proteins c-met