Abstract
We report a case of recurrent Staphylococcus aureus bacteremia in a patient who failed vancomycin due to a vancomycin-heteroresistant strain lacking methicillin resistance. Although initial isolates were susceptible, isolates obtained after vancomycin chemotherapy were vancomycin heteroresistant. This case thus illustrates the clinical emergence of vancomycin heteroresistance.
Publication types
-
Case Reports
-
Research Support, N.I.H., Extramural
MeSH terms
-
Animals
-
Anti-Bacterial Agents / pharmacology
-
Anti-Bacterial Agents / therapeutic use*
-
Bacteremia / drug therapy*
-
Bacteremia / microbiology
-
Female
-
Humans
-
Methicillin / pharmacology
-
Middle Aged
-
Renal Dialysis
-
Staphylococcal Infections / drug therapy*
-
Staphylococcal Infections / microbiology
-
Staphylococcus aureus / isolation & purification*
-
Treatment Failure
-
Vancomycin / pharmacology
-
Vancomycin / therapeutic use*
-
Vancomycin Resistance*
Substances
-
Anti-Bacterial Agents
-
Vancomycin
-
Methicillin