Preliminary report: furunculosis and hypoferraemia

Lancet. 1990 Aug 25;336(8713):464-6. doi: 10.1016/0140-6736(90)92013-8.

Abstract

16 patients with recurrent staphylococcal furunculosis but without anaemia had significantly lower serum iron concentrations than normal laboratory reference values, 8 controls with single furuncles, or 10 controls with acne conglobata. There were no significant differences in serum glucose or iron binding capacity between the groups studied. Furunculosis resolved after 3-4 weeks' treatment with iron supplements in all but 1 patient. The relation between iron and susceptibility to infection is unclear, but merits further investigation.

MeSH terms

  • Adolescent
  • Adult
  • Blood Glucose / analysis
  • Child
  • Disease Susceptibility
  • Female
  • Ferrous Compounds / therapeutic use
  • Furunculosis / blood*
  • Furunculosis / drug therapy
  • Furunculosis / etiology
  • Humans
  • Iron Deficiencies*
  • Male
  • Prospective Studies
  • Recurrence
  • Staphylococcal Infections / blood*
  • Staphylococcal Infections / etiology
  • Time Factors

Substances

  • Blood Glucose
  • Ferrous Compounds
  • ferrous sulfate
  • ferrous fumarate