Chronic haemolytic anaemia because of pyruvate kinase (PK) deficiency in a child heterozygous for haemoglobin S and no clinical features of sickle cell disease

MeSH terms

• Adult
• Anemia, Hemolytic, Congenital Nonspherocytic / blood
• Anemia, Hemolytic, Congenital Nonspherocytic / complications
• Anemia, Hemolytic, Congenital Nonspherocytic / genetics*
• Child
• Erythrocyte Indices
• Female
• Hemoglobin, Sickle / metabolism
• Heterozygote
• Humans
• Male
• Mutation, Missense
• Oxygen / blood
• Phenotype
• Point Mutation
• Pyruvate Kinase / deficiency*
• Pyruvate Kinase / genetics
• Pyruvate Metabolism, Inborn Errors / blood
• Pyruvate Metabolism, Inborn Errors / enzymology
• Pyruvate Metabolism, Inborn Errors / genetics*
• Sickle Cell Trait / blood
• Sickle Cell Trait / complications
• Sickle Cell Trait / genetics*
• beta-Globins / genetics