Abstract
A concise synthesis of three members of the withasomnine family of natural products is reported. The synthesis features a regioselective sydnone-alkynylboronate cycloaddition followed by Suzuki cross coupling and silyl group removal, and marks the first divergent approach to this family of pyrazole based natural products.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkaloids / chemical synthesis*
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Alkaloids / chemistry*
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Biological Products / chemical synthesis
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Biological Products / chemistry
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Pyrazoles / chemical synthesis*
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Pyrazoles / chemistry*
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Stereoisomerism
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Substrate Specificity
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Sydnones / chemistry
Substances
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Alkaloids
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Biological Products
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Pyrazoles
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Sydnones