Effects of a clinical pathway on quality of care in kidney transplantation: a non-randomized clinical trial

Langenbecks Arch Surg. 2010 Jan;395(1):11-7. doi: 10.1007/s00423-009-0551-3.

Abstract

Purpose: Standardization of care is essential for improving outcome of kidney transplantation (KT). Clinical pathways (CPs) are known to standardize and improve perioperative care for a number of interventions. In transplantation medicine, however, pertinent evidence is very limited. This study evaluates effects of a CP on quality of care in KT.

Materials and methods: Consecutive patients (n=32) undergoing KT between July 2006 and August 2007 who were treated with a CP were compared to patients (n=44) treated without CP between January 2005 and June 2006. Several quality indicators regarding process and outcome were compared between groups.

Results: Quality of care was significantly higher in the CP group for the following indicators: timely removal of central venous catheters, wound drains, and Foley catheters and control of cyclosporine levels, respiratory exercising, and pain control. Median stay decreased non-significantly from 21.4 to 18.3 days. There was significantly less delayed graft function in the CP group. All other outcome indicators showed no significant differences.

Conclusions: Implementation of a CP for KT improves the quality of perioperative treatment by standardizing care. Regarding effects on outcome, no clear conclusion can be drawn. We recommend that large randomized studies are conducted to evaluate the latter issue.

Publication types

  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cadaver
  • Critical Pathways / organization & administration*
  • Female
  • Follow-Up Studies
  • Germany
  • Graft Rejection
  • Graft Survival
  • Humans
  • Kaplan-Meier Estimate
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / surgery*
  • Kidney Transplantation / methods*
  • Kidney Transplantation / mortality
  • Living Donors / statistics & numerical data
  • Male
  • Middle Aged
  • Perioperative Care / methods
  • Postoperative Complications / mortality
  • Postoperative Complications / physiopathology
  • Probability
  • Program Evaluation
  • Prospective Studies
  • Quality of Health Care*
  • Statistics, Nonparametric
  • Survival Analysis
  • Treatment Outcome