Abstract
The Blaise reaction intermediate, generated in situ from Reformatsky reagent and nitrile, reacted with propiolates in a chemo- and regioselective manner to afford 2-pyridone derivatives in good to excellent yields.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Molecular Structure
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Nitriles / chemistry*
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Organometallic Compounds / chemistry
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Propionates / chemistry*
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Pyridones / chemical synthesis*
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Pyridones / chemistry
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Stereoisomerism
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Zinc / chemistry
Substances
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Alkynes
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Nitriles
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Organometallic Compounds
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Propionates
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Pyridones
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2-hydroxypyridine
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Zinc
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propiolic acid