A novel dasatinib-sensitive RCSD1-ABL1 fusion transcript in chemotherapy-refractory adult pre-B lymphoblastic leukemia with t(1;9)(q24;q34)

Haematologica. 2009 Oct;94(10):1469-71. doi: 10.3324/haematol.2009.008094.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Amino Acid Sequence
  • Dasatinib
  • Gene Fusion / genetics
  • Genes, abl / genetics*
  • Humans
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Male
  • Molecular Sequence Data
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cells, B-Lymphoid / drug effects
  • Precursor Cells, B-Lymphoid / physiology*
  • Pyrimidines / pharmacology
  • Pyrimidines / therapeutic use*
  • Thiazoles / pharmacology
  • Thiazoles / therapeutic use*
  • Translocation, Genetic / genetics*

Substances

  • Intracellular Signaling Peptides and Proteins
  • Pyrimidines
  • RCSD1 protein, human
  • Thiazoles
  • Dasatinib