Abstract
An enantioselective synthesis of the maoecrystal V (1) carbon skeleton is described. The key transformations include arylation of a 1,3-dicarbonyl compound with a triarylbismuth(V) dichloride species, oxidative dearomatization of a phenol, and a subsequent intramolecular Diels-Alder reaction.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Catalysis
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Crystallography, X-Ray
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Cyclization
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Diterpenes / chemical synthesis*
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Diterpenes / chemistry
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Diterpenes / pharmacology
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Drugs, Chinese Herbal / chemical synthesis*
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Drugs, Chinese Herbal / chemistry
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Drugs, Chinese Herbal / pharmacology
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Isodon / chemistry
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Molecular Conformation
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Stereoisomerism
Substances
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Diterpenes
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Drugs, Chinese Herbal
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maoecrystal A