Objective: To explore the impact of micronutrients supplement on immunocyte and microelements status in HIV positive people.
Methods: Volunteers aged 25-49 years old were randomly selected and distributed into two groups. Supplement and placebo were given to the two groups. At the beginning of the trial, data on physical examination, immunocyte and microelements level in serum of the two groups were collected and showed no significant difference (P > 0.05).
Results: After 6 months, the amount of immunocyte (CD4+, CD8+, CD3+) were (2078 +/- 108) mm3, (582 +/- 75) mm3, (1287 +/- 97) mm3 in the study group while they were (1436 +/- 105) mm3, (472 +/- 61) mm3, (998 +/- 84) mm3 in the control group, with statistically significant difference (P < 0.05). Amounts of serum Zn, Ca, Mg, Fe showed (144.89 +/- 9.78) micromol/L, (1.89 +/- 0.19) micromol/L, (1.68 +/- 0.12) micromol/L, (152.61 +/- 8.94) micromol/L in the study group and they were (102.67 +/- 5.45) micromol/L, (1.13 +/- 0.07) micromol/L, (0.85 +/- 0.05) micromol/L, (89.24 +/- 3.91) micromol/L in the control group, with statistically significant difference (P < 0.05).
Conclusion: Supplementation of micronutrients could increase the levels of Zn, Ca, Mg, Fe so as to increase the immune function in people living with HIV.