Abstract
We compared the results of the tuberculin skin test with the results of the QuantiFERON-TB Gold In-Tube (QFT-GIT) assay among 182 low-risk healthcare workers. Overall agreement and specificity were high, but the tests did not agree on positive results. Only 2 of 5 positive QFT-GIT assay results could be confirmed with repeat analyses. Indeterminate results were associated with potential immunosuppression.
Publication types
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Comparative Study
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Evaluation Study
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Research Support, N.I.H., Extramural
MeSH terms
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Health Personnel*
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Humans
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Incidence
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Interferon-gamma / blood*
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Latent Tuberculosis / diagnosis*
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Latent Tuberculosis / epidemiology
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Latent Tuberculosis / microbiology
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Mycobacterium tuberculosis / immunology*
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Reagent Kits, Diagnostic*
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Reproducibility of Results
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Sensitivity and Specificity
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Tuberculin Test / methods*
Substances
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Reagent Kits, Diagnostic
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Interferon-gamma