Oligonucleotide probe for detection of the enteropathogenic Escherichia coli (EPEC) adherence factor of localized adherent EPEC

J Clin Microbiol. 1990 Dec;28(12):2842-4. doi: 10.1128/jcm.28.12.2842-2844.1990.

Abstract

The enteropathogenic Escherichia coli adherence factor (EAF) probe detects isolates of enteropathogenic E. coli that exhibit localized adherence to HEp-2 cells. A 21-base oligonucleotide probe was constructed on the basis of a sequence from within the 1-kb EAF probe and was shown to have greater sensitivity and specificity than the EAF fragment probe in detecting localized adherent E. coli.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adhesins, Escherichia coli
  • Bacterial Adhesion
  • Bacterial Outer Membrane Proteins / genetics*
  • Bacterial Outer Membrane Proteins / isolation & purification
  • Base Sequence
  • DNA Probes*
  • DNA, Bacterial / genetics
  • Escherichia coli / genetics*
  • Escherichia coli / pathogenicity
  • Humans
  • Molecular Sequence Data

Substances

  • Adhesins, Escherichia coli
  • Bacterial Outer Membrane Proteins
  • DNA Probes
  • DNA, Bacterial