[Aseptic osteonecrosis of the femoral head in children with sickle-cell disease]

Sante. 2008 Oct-Dec;18(4):231-3.
[Article in French]

Abstract

Purpose: To identify the epidemiological, clinical and therapeutic aspects of hip-joint disorders in children with sickle cell disease, to point out the diagnostic problems, and to stress the necessity of early diagnosis for optimal outcome.

Material and methods: This retrospective study, conducted from January 1987 through December 2006, included children with at least one haemoglobin S gene and hospitalised for osteonecrosis of the femoral head. Ficat staging was used.

Results: The study included 14 children (12 boys and 2 girls) with a mean age of 14 years, all hospitalised and treated for osteonecrosis of the femoral head during the study period 8 SS and 6 SC. Osteonecrosis of the femoral head was diagnosed at Ficat stage 3 in 8 cases and at stage 4 in 6. Ten children (8 at stage 3 and 2 at stage 4) had orthopaedic treatment (continuous traction for 30 days and then a Thomas's splint for a mean 14 months). Outcome was good for 6 of the stage-3 cases (mean follow-up period 9 years) and poor for the other patients with purely orthopaedic treatment (mean follow-up period 11 years). Four children at stage 4 underwent surgery (varus osteotomy, immobilization in a cast for 8 weeks, and then Thomas's splint for a mean 12 months) with good results (mean follow-up period 10 years).

Conclusion: Early diagnosis, assisted by computed tomography, magnetic resonance imaging or scintigraphy, makes it possible to provide better treatment and preserve hip function.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Anemia, Sickle Cell / complications*
  • Female
  • Femur Head Necrosis / diagnosis
  • Femur Head Necrosis / epidemiology
  • Femur Head Necrosis / etiology*
  • Femur Head Necrosis / therapy
  • Humans
  • Male
  • Retrospective Studies