NMR and conformational studies of new 5-phenylpyrrole-carboxamide derivatives

Magn Reson Chem. 2009 Dec;47(12):1101-9. doi: 10.1002/mrc.2524.

Abstract

The 1H and 13C NMR resonances of 22 5-(5-substituted-2-nitrophenyl)-1H-pyrrole-2-carboxamides, 22 5-(5-substituted-2-aminophenyl)-1H-pyrrole-2-carboxamides, and 9 5-phenyl-1H-pyrrole-2-carboxamides were assigned completely using the concerted application of one- and two-dimensional experiments (DEPT, gs-HMQC and gs-HMBC). NOE studies and conformational analysis confirm the preferred conformations of such compounds.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Carbon Isotopes
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Protons
  • Pyrazoles / chemical synthesis
  • Pyrazoles / chemistry*
  • Reference Standards
  • Stereoisomerism

Substances

  • Carbon Isotopes
  • Protons
  • Pyrazoles