Treatment of tardive dyskinesia with aripiprazole

Neurotox Res. 2010 May;17(4):432-4. doi: 10.1007/s12640-009-9123-0. Epub 2009 Oct 14.

Abstract

Tardive dyskinesia (TD) is a severe and potential irreversible side effect of antipsychotic treatment. Treatment of established TD is often unsuccessful. In this article, we report three cases of psychogeriatric patients who suffered from TD as a side effect of long-term treatment with haloperidol that resolved after switching treatment to aripiprazole. Potential psychopharmacological mechanisms explaining this finding are briefly discussed.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Aripiprazole
  • Dyskinesia, Drug-Induced / drug therapy*
  • Female
  • Humans
  • Male
  • Mood Disorders / drug therapy
  • Piperazines / therapeutic use*
  • Quinolones / therapeutic use*

Substances

  • Antipsychotic Agents
  • Piperazines
  • Quinolones
  • Aripiprazole