Interaction of 5HTTLPR and marijuana use on property offending

Biodemography Soc Biol. 2009;55(1):93-102. doi: 10.1080/19485560903054762.

Abstract

This study uses data from the National Longitudinal Study of Adolescent Health to examine whether a polymorphism in the serotonin transporter gene (SHTTLPR) moderates the effects of marijuana use on property offending. The results reveal that 5HTTLPR interacts with marijuana use to predict significantly higher levels of property offending for African American females. The interaction coefficient is not statistically significant for Caucasian males, African American males, or Caucasian females. These findings suggest that marijuana use is associated only with higher levels of property offending among African American females who carry one or more copies of the 5HTTLPR short allele.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Alleles
  • Antisocial Personality Disorder / epidemiology
  • Antisocial Personality Disorder / genetics*
  • Black or African American / genetics
  • Black or African American / statistics & numerical data
  • Child
  • Crime / statistics & numerical data*
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Marijuana Smoking / epidemiology
  • Marijuana Smoking / genetics*
  • Multivariate Analysis
  • Polymorphism, Genetic*
  • Prevalence
  • Risk Assessment
  • Risk Factors
  • Serotonin Plasma Membrane Transport Proteins / genetics*
  • Surveys and Questionnaires
  • United States / epidemiology
  • Young Adult

Substances

  • Serotonin Plasma Membrane Transport Proteins