The coastal zone of the disused industrial site of Bagnoli, has been studied since 1999 in order to highlight chemical and ecological features of pollution, mainly due to a steel plant. This further study was performed in order to check the foraminiferal response to changes in sediment grain-size and contaminant concentrations and to recognise the actual effects of the environmental stress determined by industrial pollution on the foraminiferal assemblages. This was attained by considering a wider area than in the previous studies so as to recognise the possible reference conditions. Very high contamination, mainly due to Cu, Fe, Hg, Mn, Ni, Pb, Zn and PAHs, was recorded in the marine sediments close to the steel plant. Contaminant concentrations and sediment composition were recognised as important factors influencing the foraminiferal response by means of statistical analysis. The foraminiferal abnormality index (FAI) is positively correlated with heavy metals concentration, exceeding the natural threshold in front of the plant. Furthermore, increasing pollution levels correspond to the increase of pollution-tolerant species in the assemblage.