[Familial clustering, genetic roots and insights into the pathogenesis of autoimmune diseases]

Z Rheumatol. 2009 Nov;68(9):758-62. doi: 10.1007/s00393-009-0556-x.
[Article in German]

Abstract

Genome-wide association studies have dramatically increased our knowledge about the genetic contribution to autoimmune diseases. The identified genes are indicators for signal transduction pathways involved in disease pathogenesis and could contribute to potential new therapeutic approaches.

Publication types

  • English Abstract

MeSH terms

  • Autoimmune Diseases / diagnosis
  • Autoimmune Diseases / genetics*
  • Cluster Analysis*
  • Genetic Linkage / genetics*
  • Genetic Markers / genetics*
  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing / methods*
  • Heterozygote
  • Humans
  • Models, Genetic
  • Polymorphism, Single Nucleotide / genetics*

Substances

  • Genetic Markers