Rhizomucor variabilis var. regularior and Hormographiella aspergillata infections in a leukemic bone marrow transplant recipient with refractory neutropenia

Mayssa M Abuali; Roberto Posada; Gustavo Del Toro; Elizabeth Roman; Rama Ramani; Sudha Chaturvedi; Vishnu Chaturvedi; Vincent J LaBombardi

doi:10.1128/JCM.00305-09

Rhizomucor variabilis var. regularior and Hormographiella aspergillata infections in a leukemic bone marrow transplant recipient with refractory neutropenia

J Clin Microbiol. 2009 Dec;47(12):4176-9. doi: 10.1128/JCM.00305-09. Epub 2009 Oct 21.

Authors

Mayssa M Abuali¹, Roberto Posada, Gustavo Del Toro, Elizabeth Roman, Rama Ramani, Sudha Chaturvedi, Vishnu Chaturvedi, Vincent J LaBombardi

Affiliation

¹ Pediatric Infectious Diseases, Mount Sinai Medical Center, New York, New York, USA. [email protected]

Abstract

Rhizomucor variabilis and Hormographiella aspergillata rarely cause human infections. This report details a fatal case of a 14-year-old female with leukemia posthematopoietic cell transplant and relapse with refractory pancytopenia. The patient first developed an R. variabilis var. regularior palate infection and later developed a cutaneous H. aspergillata infection while on posaconazole and caspofungin therapy.

Publication types

Case Reports

MeSH terms

Adolescent
Bone Marrow Transplantation / adverse effects*
Coprinus* / classification
Coprinus* / isolation & purification
Dermatomycoses / diagnosis
Dermatomycoses / microbiology
Fatal Outcome
Female
Humans
Leukemia, Myeloid, Acute / complications
Leukemia, Myeloid, Acute / therapy
Mucormycosis / diagnosis
Mucormycosis / microbiology
Mycoses* / diagnosis
Mycoses* / microbiology
Neutropenia / complications*
Palate / microbiology
Rhizomucor* / classification
Rhizomucor* / isolation & purification