Serum retinol-binding protein 4 (RBP4) and retinol in a cohort of borderline obese women with and without gestational diabetes

Clin Biochem. 2010 Feb;43(3):320-3. doi: 10.1016/j.clinbiochem.2009.10.013. Epub 2009 Oct 24.

Abstract

Objectives: To evaluate whether serum RBP4 correlates with gestational diabetes mellitus (GDM) in a cohort of borderline obese (BMI>30) pregnant women.

Design and methods: Serum RBP4 and retinol were measured in pregnant women with (n=12) and without (n=10) GDM.

Results: RBP4, retinol and RBP4:retinol molar ratio were not different between the groups and were not associated with markers of insulin resistance.

Conclusions: GDM is not associated with RBP4 or retinol among borderline obese pregnant women.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Animals
  • Blood Glucose / metabolism
  • Diabetes, Gestational / blood*
  • Female
  • Humans
  • Insulin / blood
  • Leptin / blood
  • Obesity / blood*
  • Pregnancy
  • Retinol-Binding Proteins, Plasma / metabolism*
  • Vitamin A / blood*
  • Young Adult

Substances

  • Blood Glucose
  • Insulin
  • Leptin
  • RBP4 protein, human
  • Retinol-Binding Proteins, Plasma
  • Vitamin A