Abstract
Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.
Publication types
-
Evaluation Study
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Adolescent
-
Adult
-
Antigens, Viral / blood*
-
Child
-
Child, Preschool
-
Disease Outbreaks*
-
False Negative Reactions
-
Humans
-
Infant
-
Influenza A Virus, H1N1 Subtype / isolation & purification*
-
Influenza, Human / blood
-
Influenza, Human / diagnosis*
-
Polymerase Chain Reaction
-
Sensitivity and Specificity
-
Serologic Tests
-
Young Adult