Abstract
The follicular development in the cow occurs in a wave-like pattern, and it takes place also during pregnancy. In the cow, Equine Chorionic Gonadotropin (eCG) is used for superovulation, but a decrease in total fertility has been reported, likely because of its immunogenic properties in species other than equine. In this regard, immune response has been implicated in follicular growth, ovulation, and placental development. So, aims of our study are to test the safety of eCG administered during pregnancy and characterize the ovarian activity, the quality of oocytes, the hormonal status, and interleukin levels in eCG-treated pregnant cows.
MeSH terms
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Animals
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Cattle
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Estradiol / blood
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Female
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Gonadotropins, Equine / administration & dosage*
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Gonadotropins, Equine / adverse effects
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Horses
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Interleukin-2 / biosynthesis
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Interleukin-2 / blood
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Interleukin-4 / biosynthesis
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Interleukin-4 / blood
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Oocytes / drug effects
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Oocytes / growth & development
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Oocytes / immunology
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Oocytes / metabolism
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Ovarian Follicle / drug effects*
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Ovarian Follicle / growth & development*
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Ovarian Follicle / immunology
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Ovarian Follicle / metabolism
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Ovulation Induction / adverse effects
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Ovulation Induction / methods*
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Ovulation Induction / veterinary*
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Pregnancy
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Pregnancy, Animal / drug effects*
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Pregnancy, Animal / immunology
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Pregnancy, Animal / metabolism
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Progesterone / blood
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Random Allocation
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Time Factors
Substances
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Gonadotropins, Equine
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Interleukin-2
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Interleukin-4
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Progesterone
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Estradiol