Sun proteins enlighten nuclear movement in development

Neuron. 2009 Oct 29;64(2):147-9. doi: 10.1016/j.neuron.2009.10.010.

Abstract

Regulation of nuclear movement is a critical event in neurogenesis and neuronal migration during brain development. In this issue of Neuron, Zhang et al. identify a role for SUN and the KASH-domain-containing nuclear membrane proteins as the long-sought linker between microtubules and the nucleus during brain development.

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain / cytology
  • Brain / embryology*
  • Cell Nucleus / genetics
  • Cell Nucleus / metabolism*
  • Humans
  • Nuclear Proteins / genetics
  • Nuclear Proteins / metabolism*
  • Protein Transport / genetics
  • Protein Transport / physiology*

Substances

  • Nuclear Proteins