Abstract
In this point of view we discuss the role of co-activators and co-repressors of miRNA precursors maturation, the possibility that their functions are post translationally regulated by different signaling pathways, and their potential role in the miRNA-dependent control of cell proliferation and differentiation.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Cell Differentiation
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Cell Proliferation
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Co-Repressor Proteins / physiology
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Humans
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MicroRNAs / metabolism*
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RNA Precursors / metabolism*
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RNA Processing, Post-Transcriptional*
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Ribonuclease III / metabolism
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Signal Transduction
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Transcription Factors / physiology
Substances
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Co-Repressor Proteins
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MicroRNAs
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RNA Precursors
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Transcription Factors
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DROSHA protein, human
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Ribonuclease III