Cardiac involvement in patients of systemic sclerosis

Indian J Dermatol. 2008;53(4):215-6. doi: 10.4103/0019-5154.44801.

Abstract

Background: Systemic sclerosis is a multi-systemic autoimmune disorder. Cardiac involvement by the disease, although not included in the diagnostic criteria, may be seen either clinically, histologically or may be revealed by various investigative modalities.

Purpose: To see the profile of cardiac involvement in patients of systemic sclerosis.

Materials and methods: Forty-seven patients of systemic sclerosis were included in the study. After taking a complete history and doing a detailed physical examination, the patients were submitted to electrocardiogram ECG (all leads), echocardiography and x-ray chest. Furst's organ indices scoring system for cardiac involvement was followed.

Findings: Forty-seven patients of systemic sclerosis were included in the study. Five females gave a history of palpitations. A loud pulmonic heart sound was heard in 1. Arrhythmias were observed in 5 patients. Significantly, echocardiography revealed valvular involvement in 5 patients. Left ventricular hypertrophy was seen in 2 patients.

Conclusions: In our patients, cardiac involvement was rare. In contrast to other studies, valvular involvement was a prominent feature.

Limitations: Complete evaluation for arrhythmias with 24-h Holter monitor was not used.

Keywords: Cutaneous metastases; cardiac involvement; melanoma; systemic sclerosis; ventricular hypertrophy.