[A case of pulmonary metastases from bladder cancer, suspected of recurrent Wegener's granulomatosis]

Nihon Kokyuki Gakkai Zasshi. 2009 Oct;47(10):943-6.
[Article in Japanese]

Abstract

A 26-year-old-woman was given a diagnosis of Wegener's granulomatosis and began treatment by both prednisolone and cyclophosphamide at another institution. She was then admitted to our hospital due to progressive multiple pulmonary nodules. A diagnosis of pulmonary metastases from bladder cancer was established with radiological and histological examinations obtained by transbronchial lung biopsy (TBLB) and transurethral resection of the bladder tumor (TUR-Bt). She had already received a total dose of 120 g of cyclophosphamide, which could be related to the development of bladder cancer. On detecting multiple pulmonary nodules in patients with Wegener's granulomatosis treated with cyclophosphamide, it is necessary to consider the possibility of pulmonary metastases form urinary bladder cancer.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Carcinoma, Transitional Cell / chemically induced
  • Carcinoma, Transitional Cell / pathology*
  • Cyclophosphamide / adverse effects
  • Diagnosis, Differential
  • Female
  • Granulomatosis with Polyangiitis / diagnosis*
  • Granulomatosis with Polyangiitis / drug therapy
  • Humans
  • Lung Neoplasms / secondary*
  • Recurrence
  • Urinary Bladder Neoplasms / chemically induced
  • Urinary Bladder Neoplasms / pathology*

Substances

  • Cyclophosphamide