The only potentially curative treatment available for gastric adenocarcinoma is surgical resection. However, many controversies exist regarding treatment strategy, including whether the laparoscopic approach is appropriate. Many reports of laparoscopic techniques for cancer resection have shown oncologic equivalency to the open technique, with the known benefits of the minimally invasive approach, such as decreased pain, length of hospital stay, blood loss, and complications. The Eastern experience with laparoscopic gastrectomy has been extensive, associated with the increased incidence of early gastric cancers. However, in the West, laparoscopic approaches for gastric cancer have been more slowly accepted, largely due to the lower incidence of gastric cancer in this part of the world. Therefore, we aimed to review the technical feasibility and oncologic efficacy of the laparoscopic versus open approach to resection for gastric adenocarcinoma in the West. Review of the literature demonstrates that laparoscopic gastrectomy is a safe technique with short-term oncologic results that are equivalent in terms of margin status and lymph node retrieval and are associated with additional benefits of the minimally invasive approach, although long-term follow up is necessary. Laparoscopic gastrectomy for adenocarcinoma, similar to findings in the East, resulted in a decreased length of hospital stay, decreased narcotic use, fewer complications, and equivalent short-term oncologic outcomes. It appears that the minimally invasive approach for gastric resection of adenocarcinoma is safe and satisfies oncologic requirements, and is justified for use in selected patients.