Indirect mechanisms of carcinogenesis via downregulation of PTEN function

Adv Enzyme Regul. 2010;50(1):112-8. doi: 10.1016/j.advenzreg.2009.10.015. Epub 2009 Nov 4.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Transformation, Neoplastic*
  • Down-Regulation*
  • Endosomal Sorting Complexes Required for Transport / genetics
  • Endosomal Sorting Complexes Required for Transport / metabolism
  • GTPase-Activating Proteins / genetics
  • GTPase-Activating Proteins / metabolism
  • Humans
  • Myosin Type V / genetics
  • Myosin Type V / metabolism
  • Nedd4 Ubiquitin Protein Ligases
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / metabolism
  • Neoplasms / genetics
  • Neoplasms / metabolism
  • PDZ Domains
  • PTEN Phosphohydrolase / genetics
  • PTEN Phosphohydrolase / metabolism*
  • Phosphoproteins / genetics
  • Phosphoproteins / metabolism
  • Protein Binding
  • Signal Transduction / physiology
  • Sodium-Hydrogen Exchangers / genetics
  • Sodium-Hydrogen Exchangers / metabolism
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism
  • Ubiquitin-Protein Ligases / genetics
  • Ubiquitin-Protein Ligases / metabolism
  • X-Linked Inhibitor of Apoptosis Protein / genetics
  • X-Linked Inhibitor of Apoptosis Protein / metabolism

Substances

  • Endosomal Sorting Complexes Required for Transport
  • GTPase-Activating Proteins
  • Neoplasm Proteins
  • Phosphoproteins
  • Sodium-Hydrogen Exchangers
  • Tumor Suppressor Proteins
  • X-Linked Inhibitor of Apoptosis Protein
  • sodium-hydrogen exchanger regulatory factor
  • Nedd4 Ubiquitin Protein Ligases
  • Ubiquitin-Protein Ligases
  • PTEN Phosphohydrolase
  • PTEN protein, human
  • Myosin Type V