Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells

Adv Enzyme Regul. 2010;50(1):285-307. doi: 10.1016/j.advenzreg.2009.10.016. Epub 2009 Nov 4.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antineoplastic Agents* / pharmacology
  • Antineoplastic Agents* / therapeutic use
  • Breast Neoplasms* / metabolism
  • Breast Neoplasms* / pathology
  • Breast Neoplasms* / therapy
  • Calcium-Calmodulin-Dependent Protein Kinases / genetics
  • Calcium-Calmodulin-Dependent Protein Kinases / metabolism
  • Cell Line, Tumor
  • Drug Resistance / physiology*
  • Enzyme Activation
  • Female
  • Humans
  • Mitogen-Activated Protein Kinases / genetics
  • Mitogen-Activated Protein Kinases / metabolism
  • Neoplasm Metastasis
  • Neoplastic Stem Cells* / drug effects
  • Neoplastic Stem Cells* / metabolism
  • PTEN Phosphohydrolase / genetics
  • PTEN Phosphohydrolase / metabolism
  • Phosphatidylinositol 3-Kinases / metabolism
  • Signal Transduction / physiology*

Substances

  • Antineoplastic Agents
  • Phosphatidylinositol 3-Kinases
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Mitogen-Activated Protein Kinases
  • PTEN Phosphohydrolase