Research letter: Psychotherapy increases brain serotonin 5-HT1A receptors in patients with major depressive disorder

Psychol Med. 2010 Mar;40(3):523-8. doi: 10.1017/S0033291709991607. Epub 2009 Nov 11.

Authors

H Karlsson, J Hirvonen, J Kajander, J Markkula, H Rasi-Hakala, J K Salminen, K Någren, S Aalto, J Hietala

PMID: 19903365
DOI: 10.1017/S0033291709991607

No abstract available

Publication types

Letter
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Analysis of Variance
Antidepressive Agents, Second-Generation / therapeutic use
Brain / diagnostic imaging*
Brain / drug effects
Brain / metabolism*
Brain Chemistry / drug effects
Depressive Disorder, Major / metabolism*
Depressive Disorder, Major / therapy*
Female
Finland
Fluoxetine / therapeutic use
Humans
Imaging, Three-Dimensional / methods
Male
Positron-Emission Tomography / methods
Psychotherapy / methods*
Receptors, Serotonin, 5-HT1 / drug effects
Receptors, Serotonin, 5-HT1 / metabolism*

Substances

Antidepressive Agents, Second-Generation
Receptors, Serotonin, 5-HT1
Fluoxetine