Toward depression remission: balancing efficacy and tolerability

J Clin Psychiatry. 2009 Oct;70(10):e36. doi: 10.4088/JCP.8118br1c.

Abstract

Emerging research has found that different neurotransmitters play roles in the regulation of depressive symptomatology and adverse events associated with antidepressant treatment. Residual depressive symptoms and adverse events can lead to noncompliance and the discontinuation of treatment. Several approaches may help clinicians address residual symptoms and tolerability issues in patients with depression.

Publication types

  • Review

MeSH terms

  • Antidepressive Agents / adverse effects*
  • Antidepressive Agents / therapeutic use*
  • Depressive Disorder / drug therapy*
  • Humans
  • Patient Compliance
  • Treatment Outcome

Substances

  • Antidepressive Agents